Highly accurate and reliable way to discover Transcription Factor Binding Motifs, alternative promoters and new biomarkers by determining the cause of transcription.
The purpose of CAGE was to create a highly accurate technology to comprehensively map the vast majority of human transcription starting sites and their promoters. We succeeded. CAGE is a novel and more accurate technology than microarray and RNA-seq, and we want to share our success.
Up-regulated expression in some genes can be due to the presence of binding sites for some specific transcription factors.